Progression rate to diabetes mellitus and association between sleep factors, serum uric acid level, and HbA1c level in pre-diabetic people

ธัญญรัตน์ อโนทัยสินทวี; Thunyarat Anothaisintawee; ดำรงรัตน์ เลิศรัตนานนท์; Dumrongrat Lertrattananon; อัมรินทร์ ทักขิญเสถียร; Ammarin Thakkinstian;
Date: 2560-01
Abstract
Diabetes mellitus (DM) is the major public health burden in Thailand. DM is the significant risk factors of cardiovascular disease, end stage renal disease and cancer. Therefore, to decrease morbidity and mortality from diabetic complications, prevention of DM is an important issue. Insulin resistance and pancreatic β-cell dysfuction are the major mechanisms of developing DM. These 2 mechanisms lead to abnormal glucose regulation, called prediabetes that comprises of impaired fasting glucose or impaired glucose tolerance. Previous evidences found that prediabetes is a significant risk factor of DM. Around 60% of diabetic patients had prediabetes 5 years before developing DM. Until now, there has been no study that investigate about the progression rate to DM in Thai prediabetes patients. In addition, currently, there is new proposed risk factors of DM such as serum uric acid and sleep factors. Therefore, this study aims to estimate the progression rate to DM and assess the association between sleep factors, serum uric acid, and HbA1C level.
Copyright ผลงานวิชาการเหล่านี้เป็นลิขสิทธิ์ของสถาบันวิจัยระบบสาธารณสุข หากมีการนำไปใช้อ้างอิง โปรดอ้างถึงสถาบันวิจัยระบบสาธารณสุข ในฐานะเจ้าของลิขสิทธิ์ตามพระราชบัญญัติสงวนลิขสิทธิ์สำหรับการนำงานวิจัยไปใช้ประโยชน์ในเชิงพาณิชย์
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