The study aims to a review of measures and policies on gender and AIDS in Thailand The author would like to propose that from the beginning, the management of the spread of HIV/AIDS and interest around AIDS issues has been characterized by social bias towards marginalized groups, such as gays, prisoners, drafted soldiers, drug users, women in prostitution, laborers who are considered by society as lower class, and women, who, in patriarchal society, are considered the inferior sex. The role of middle class men, especially white men, as husbands and partners in the spread of HIV/AIDS is typically overlooked (whether intentionally or through the prejudice inherent in the structure of patriarchy). A great number of men engage in promiscuous sexual behavior and fail to protect themselves, and may in fact be considered a large group with high-risk behavior. Although twenty years have passed, the state still hasn’t made a serious effort to address issues involving this group. This is despite the fact that data shows that more than half of the people infected with HIV/AIDS are women who have had a sexual relationship with only one man their entire lives, which should be a good indicator of where the problem lies. Education around and/or responses to the HIV/AIDS pandemic must include consideration of the importance of sexuality and related issues. because the biological conditions of women make them more susceptible to infection. It’s because the socially constructed context of gender disempowers women socially, culturally, economically, and politically and makes infection from men easy and with severe impacts. Social constructs of gender have led hundreds of thousands of women to become infected and hundreds of thousands more to take on the burden of caring for both male and female family members who are infected.The unequal power relations between developed and developing nations places science and technology under the control of Western scientists who adhere to mainstream patriarchal ideology. Smaller states tend to reproduce these patriarchal structures and accept the world economic order in the era of globalization. This makes trans-national corporations able to control access to the medicine and vaccines necessary to prevent and treat AIDS. Under developed or developing countries are not able to handle the problem alone due to its magnitude and the economic power and capacity required to access knowledge and information. The lack of clarity around the origins of AIDS leads to further problems. Scientists outside the mainstream both in and outside the West come up against barriers in transmitting information and research findings in wider circles. There is little or no space for natural or alternative methods of treatment and prevention within the larger global media. Knowledge and information concerning women, AIDS, and gender on individual, family, and community levels, as well as among NGOs, groups of people living with AIDS, government, and inter-government agencies, is still quite lacking. It is necessary to work together at every level to conduct wider research and create discourse on the body of knowledge to be used as a conceptual basis to advocate for the equal rights, creativity, and sustainable development necessary to ensure the human security of both men and women.