Dapsone Hypersensitivity Syndrome: Report of a Patient, Resident in Banfang District, Khon Kaen

บุญชัย ตระกูลขจรศักดิ์; Boonchai Trakulkajornsak;
Date: 2550
Abstract
Dapsone hypersensitivity syndrome (DHS) is a condition rarely reported in Thailand. Recently, during the period from January 1 to August 8, 2007, a 40-year-old male patient, among the five cases on multidrug therapy (containing dapsone) for treatment of leprosy, developed DHS (fever, maculopapular rash, hepatitis, lymphadenopathy and pneumonitis) eight weeks from the start of the treatment. Prompt drug withdrawal, administration of corticosteroid and supportive treatment led to his rapid are recovery; he was discharged on the 11th day of hospitalization. The patient is likely to have represented the second reported case of its kind in Thailand. The author is publicizing this case as a warning to physicians who chance the use of dapsone; they must be aware that the severe and potentially fatal side-effects of such a hypersensitivity syndrome is not so rare
Copyright ผลงานวิชาการเหล่านี้เป็นลิขสิทธิ์ของสถาบันวิจัยระบบสาธารณสุข หากมีการนำไปใช้อ้างอิง โปรดอ้างถึงสถาบันวิจัยระบบสาธารณสุข ในฐานะเจ้าของลิขสิทธิ์ตามพระราชบัญญัติสงวนลิขสิทธิ์สำหรับการนำงานวิจัยไปใช้ประโยชน์ในเชิงพาณิชย์
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