Abstract
To examine the correlation between capillary whole blood glucose and plasma glucose
determined by a capillary glucose biosensor (Accu-Chek Advantage) and the standard
venous glucose oxidase test, a descriptive cross-sectional study was conducted on
267 diabetic patients who attended the DM Clinic of Srichiangmai Hospital from August
to September 2007. A pair of finger-tip capillary whole blood and venous blood samples were collected from each subject for glucose determination by the capillary glucose biosensor
(Accu-Chek Advantage) and the standard venous glucose oxidase test. Correlation
of the results from both methods was performed by using the correlation coefficient
and linear regression methods.
The mean level of capillary whole blood glucose was 156.08 mg/dl, and of plasma
glucose, 171.73 mg/dl. The mean plasma glucose level was 9.1 percent higher than that of
the capillary whole blood. The correlation coefficient (r) of the two methods was 0.913.
The plasma glucose level may be estimated from the known capillary whole blood glucose
level by the linear regression equation: Y = 0.824X + 14.574.
The glucose levels determined by the capillary glucose biosensor (Accu-Chek Advantage)
correlated well with those obtained by the standard method (Glucose oxidase
test) which represents the actual blood glucose level. Accu-Chek Advantage can be used
for both DM screening and patient follow-up; the actual glucose level, which was determined
by the glucose oxidase technique, can be calculated using the linear regression
equation.
